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Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import
BACKGROUND: Integration of human immunodeficiency virus type 1 (HIV-1) into a host cell chromosome is an essential step under the control of the viral integrase (IN). Although this enzyme is necessary and sufficient to catalyze the integration reaction in vitro, cellular cofactors are involved in th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286403/ https://www.ncbi.nlm.nih.gov/pubmed/22176773 http://dx.doi.org/10.1186/1742-4690-8-104 |