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Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

BACKGROUND: The receptor tyrosine kinase family includes many transmembrane proteins with diverse physiological and pathophysiological functions. The involvement of tyrosine kinase signaling in promoting a more aggressive tumor phenotype within the context of chemotherapeutic evasion is gaining reco...

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Detalles Bibliográficos
Autores principales: Marshall, Aaron M, McClaine, Rebecca J, Gurusamy, Devikala, Gray, Jerilyn K, Lewnard, Kara E, Khan, Sohaib A, Waltz, Susan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286430/
https://www.ncbi.nlm.nih.gov/pubmed/22226043
http://dx.doi.org/10.1186/1476-4598-11-2