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Comparisons against baseline within randomised groups are often used and can be highly misleading
BACKGROUND: In randomised trials, rather than comparing randomised groups directly some researchers carry out a significance test comparing a baseline with a final measurement separately in each group. METHODS: We give several examples where this has been done. We use simulation to demonstrate that...
Autores principales: | Bland, J Martin, Altman, Douglas G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286439/ https://www.ncbi.nlm.nih.gov/pubmed/22192231 http://dx.doi.org/10.1186/1745-6215-12-264 |
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