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Comparisons against baseline within randomised groups are often used and can be highly misleading

BACKGROUND: In randomised trials, rather than comparing randomised groups directly some researchers carry out a significance test comparing a baseline with a final measurement separately in each group. METHODS: We give several examples where this has been done. We use simulation to demonstrate that...

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Detalles Bibliográficos
Autores principales: Bland, J Martin, Altman, Douglas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286439/
https://www.ncbi.nlm.nih.gov/pubmed/22192231
http://dx.doi.org/10.1186/1745-6215-12-264