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Visualization of Murine Intranasal Dosing Efficiency Using Luminescent Francisella tularensis: Effect of Instillation Volume and Form of Anesthesia

Intranasal instillation is a widely used procedure for pneumonic delivery of drugs, vaccine candidates, or infectious agents into the respiratory tract of research mice. However, there is a paucity of published literature describing the efficiency of this delivery technique. In this report we have u...

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Detalles Bibliográficos
Autores principales: Miller, Mark A., Stabenow, Jennifer M., Parvathareddy, Jyothi, Wodowski, Andrew J., Fabrizio, Thomas P., Bina, Xiaowen R., Zalduondo, Lillian, Bina, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286442/
https://www.ncbi.nlm.nih.gov/pubmed/22384012
http://dx.doi.org/10.1371/journal.pone.0031359