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In Vitro Study of Novel Collagenase (XIAFLEX®) on Dupuytren's Disease Fibroblasts Displays Unique Drug Related Properties

Dupuytren's disease (DD) is a benign, fibroproliferative disease of the palmar fascia, with excessive extracellular matrix (ECM) deposition and over-production of cytokines and growth factors, resulting in digital fixed flexion contractures limiting hand function and patient quality of life. Su...

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Detalles Bibliográficos
Autores principales: Syed, Farhatullah, Thomas, Alexis N., Singh, Subir, Kolluru, Venkatesh, Emeigh Hart, Susan G., Bayat, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286458/
https://www.ncbi.nlm.nih.gov/pubmed/22384021
http://dx.doi.org/10.1371/journal.pone.0031430