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In Vitro Study of Novel Collagenase (XIAFLEX®) on Dupuytren's Disease Fibroblasts Displays Unique Drug Related Properties
Dupuytren's disease (DD) is a benign, fibroproliferative disease of the palmar fascia, with excessive extracellular matrix (ECM) deposition and over-production of cytokines and growth factors, resulting in digital fixed flexion contractures limiting hand function and patient quality of life. Su...
Autores principales: | Syed, Farhatullah, Thomas, Alexis N., Singh, Subir, Kolluru, Venkatesh, Emeigh Hart, Susan G., Bayat, Ardeshir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286458/ https://www.ncbi.nlm.nih.gov/pubmed/22384021 http://dx.doi.org/10.1371/journal.pone.0031430 |
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