Analyzing Thioflavin T Binding to Amyloid Fibrils by an Equilibrium Microdialysis-Based Technique

A new approach for the determination of the amyloid fibril – thioflavin T (ThT) binding parameters (the number of binding modes, stoichiometry, and binding constants of each mode) is proposed. This approach is based on the absorption spectroscopy determination of the concentration of free and bound...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Irina M., Sulatskaya, Anna I., Uversky, Vladimir N., Turoverov, Konstantin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286464/
https://www.ncbi.nlm.nih.gov/pubmed/22383971
http://dx.doi.org/10.1371/journal.pone.0030724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286464/
https://www.ncbi.nlm.nih.gov/pubmed/22383971
http://dx.doi.org/10.1371/journal.pone.0030724

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