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Pharmacokinetics, metabolism and excretion of [(14)C]-lenalidomide following oral administration in healthy male subjects

PURPOSE: Assessment of the absorption, metabolism and excretion of [(14)C]-lenalidomide in healthy male subjects following a single oral dose. METHODS: Six healthy male subjects were administered a single 25 mg oral suspension dose of [(14)C]-lenalidomide. Blood (plasma), semen and excreta were coll...

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Detalles Bibliográficos
Autores principales: Chen, Nianhang, Wen, Lian, Lau, Henry, Surapaneni, Sekhar, Kumar, Gondi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286592/
https://www.ncbi.nlm.nih.gov/pubmed/22037879
http://dx.doi.org/10.1007/s00280-011-1760-3