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Melanocortin Receptor 4 Deficiency Affects Body Weight Regulation, Grooming Behavior, and Substrate Preference in the Rat

Obesity is caused by an imbalance between energy intake and expenditure and has become a major health-care problem in western society. The central melanocortin system plays a crucial role in the regulation of feeding and energy expenditure, and functional loss of melanocortin receptor 4 (MC4R) is th...

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Detalles Bibliográficos
Autores principales: Mul, Joram D., van Boxtel, Ruben, Bergen, Dylan J.M., Brans, Maike A.D., Brakkee, Jan H., Toonen, Pim W., Garner, Keith M., Adan, Roger A.H., Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286758/
https://www.ncbi.nlm.nih.gov/pubmed/21527895
http://dx.doi.org/10.1038/oby.2011.81