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Melanocortin Receptor 4 Deficiency Affects Body Weight Regulation, Grooming Behavior, and Substrate Preference in the Rat
Obesity is caused by an imbalance between energy intake and expenditure and has become a major health-care problem in western society. The central melanocortin system plays a crucial role in the regulation of feeding and energy expenditure, and functional loss of melanocortin receptor 4 (MC4R) is th...
Autores principales: | Mul, Joram D., van Boxtel, Ruben, Bergen, Dylan J.M., Brans, Maike A.D., Brakkee, Jan H., Toonen, Pim W., Garner, Keith M., Adan, Roger A.H., Cuppen, Edwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286758/ https://www.ncbi.nlm.nih.gov/pubmed/21527895 http://dx.doi.org/10.1038/oby.2011.81 |
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