Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA

Pdx1 (pancreatic and duodenal homeobox 1), Ngn3 (neurogenin 3) and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A) have been reported to bring about the transdifferentiation of pancreatic exocrine cells to beta (β) cells in vivo. We have investigated the mechanism of this pro...

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Detalles Bibliográficos
Autores principales: Akinci, Ersin, Banga, Anannya, Greder, Lucas V., Dutton, James R., Slack, Jonathan M. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286861/
https://www.ncbi.nlm.nih.gov/pubmed/22150363
http://dx.doi.org/10.1042/BJ20111678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286861/
https://www.ncbi.nlm.nih.gov/pubmed/22150363
http://dx.doi.org/10.1042/BJ20111678

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