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A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)

The canonical pathway of regulation of the GCK (germinal centre kinase) III subgroup member, MST3 (mammalian Sterile20-related kinase 3), involves a caspase-mediated cleavage between N-terminal catalytic and C-terminal regulatory domains with possible concurrent autophosphorylation of the activation...

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Detalles Bibliográficos
Autores principales: Fuller, Stephen J., McGuffin, Liam J., Marshall, Andrew K., Giraldo, Alejandro, Pikkarainen, Sampsa, Clerk, Angela, Sugden, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286863/
https://www.ncbi.nlm.nih.gov/pubmed/22229648
http://dx.doi.org/10.1042/BJ20112000