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Epstein-Barr virus Latent Membrane Protein LMP1 reduces p53 protein levels independent of the PI3K-Akt pathway

BACKGROUND: Nasopharyngeal carcinoma (NPC) is an epithelial malignancy, which commonly occurs in Southern China, Taiwan, North Africa and Southeast Asia. Nasopharyngeal carcinoma is strongly associated with Epstein-Barr virus infection. The p53 tumour suppressor protein is rarely mutated in NPC sugg...

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Detalles Bibliográficos
Autores principales: Husaini, Roslina, Ahmad, Munirah, Soo-Beng Khoo, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287105/
https://www.ncbi.nlm.nih.gov/pubmed/22185663
http://dx.doi.org/10.1186/1756-0500-4-551