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A comparison of ARMS and direct sequencing for EGFR mutation analysis and Tyrosine Kinase Inhibitors treatment prediction in body fluid samples of Non-Small-Cell Lung Cancer patients

BACKGROUND: Epidermal growth factor receptor (EGFR) mutation is strongly associated with the therapeutic effect of tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer (NSCLC). Nevertheless, tumor tissue that needed for mutation analysis is frequently unavailable. Body fluid...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Liu, Bing, Li, Xiao-Yan, Li, Jian-Jie, Qin, Hai-Feng, Tang, Chuan-Hao, Guo, Wan-Feng, Hu, Hai-Xu, Li, Sha, Chen, Cui-Jing, Gao, Hong-Jun, Liu, Xiao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287118/
https://www.ncbi.nlm.nih.gov/pubmed/22142557
http://dx.doi.org/10.1186/1756-9966-30-111