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Fractalkine/CX(3)CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death
BACKGROUND: Fractalkine/CX(3)CL1 and its cognate receptor CX(3)CR1 are abundantly expressed in the CNS. Fractalkine is an unusual C-X3-C motif chemokine that is important in neuron-microglial communication, a co-receptor for HIV infection, and can be neuroprotective. To assess the effects of fractal...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287119/ https://www.ncbi.nlm.nih.gov/pubmed/22093090 http://dx.doi.org/10.1186/1750-1326-6-78 |