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The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner

The specificity and processivity of DNA methyltransferases have important implications regarding their biological functions. We have investigated the sequence specificity of CcrM and show here that the enzyme has a high specificity for GANTC sites, with only minor preferences at the central position...

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Detalles Bibliográficos
Autores principales: Albu, Razvan F., Jurkowski, Tomasz P., Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287173/
https://www.ncbi.nlm.nih.gov/pubmed/21926159
http://dx.doi.org/10.1093/nar/gkr768