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Highly organized DnaA–oriC complexes recruit the single-stranded DNA for replication initiation

In Escherichia coli, the replication origin oriC consists of two functional regions: the duplex unwinding element (DUE) and its flanking DnaA-assembly region (DAR). ATP-DnaA molecules multimerize on DAR, unwinding DUE for DnaB helicase loading. However, DUE-unwinding mechanisms and functional struct...

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Detalles Bibliográficos
Autores principales: Ozaki, Shogo, Katayama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287180/
https://www.ncbi.nlm.nih.gov/pubmed/22053082
http://dx.doi.org/10.1093/nar/gkr832