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An unstructured 5′-coding region of the prfA mRNA is required for efficient translation

Expression of virulence factors in the human bacterial pathogen Listeria monocytogenes is almost exclusively regulated by the transcriptional activator PrfA. The translation of prfA is controlled by a thermosensor located in the 5′-untranslated RNA (UTR), and is high at 37°C and low at temperatures...

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Detalles Bibliográficos
Autores principales: Loh, Edmund, Memarpour, Faranak, Vaitkevicius, Karolis, Kallipolitis, Birgitte H., Johansson, Jörgen, Sondén, Berit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287183/
https://www.ncbi.nlm.nih.gov/pubmed/22053088
http://dx.doi.org/10.1093/nar/gkr850