Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody

The parasite Trypanosoma brucei, the causative agent of sleeping sickness across sub-Saharan Africa, depends on a remarkable U-insertion/deletion RNA editing process in its mitochondrion. A approximately 20 S multi-protein complex, called the editosome, is an essential machinery for editing pre-mRNA...

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Detalles Bibliográficos
Autores principales: Park, Young-Jun, Pardon, Els, Wu, Meiting, Steyaert, Jan, Hol, Wim G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287191/
https://www.ncbi.nlm.nih.gov/pubmed/22039098
http://dx.doi.org/10.1093/nar/gkr867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287191/
https://www.ncbi.nlm.nih.gov/pubmed/22039098
http://dx.doi.org/10.1093/nar/gkr867

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