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Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody
The parasite Trypanosoma brucei, the causative agent of sleeping sickness across sub-Saharan Africa, depends on a remarkable U-insertion/deletion RNA editing process in its mitochondrion. A approximately 20 S multi-protein complex, called the editosome, is an essential machinery for editing pre-mRNA...
Autores principales: | Park, Young-Jun, Pardon, Els, Wu, Meiting, Steyaert, Jan, Hol, Wim G. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287191/ https://www.ncbi.nlm.nih.gov/pubmed/22039098 http://dx.doi.org/10.1093/nar/gkr867 |
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