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Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2

The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly imprinted in humans, where it is a candidate for the growth retardation Silver-Russell syndrome. The MEST protein belongs to an ancient famil...

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Detalles Bibliográficos
Autores principales: MacIsaac, Julia L., Bogutz, Aaron B., Morrissy, A. Sorana, Lefebvre, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287194/
https://www.ncbi.nlm.nih.gov/pubmed/22053079
http://dx.doi.org/10.1093/nar/gkr871