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Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2
The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly imprinted in humans, where it is a candidate for the growth retardation Silver-Russell syndrome. The MEST protein belongs to an ancient famil...
Autores principales: | MacIsaac, Julia L., Bogutz, Aaron B., Morrissy, A. Sorana, Lefebvre, Louis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287194/ https://www.ncbi.nlm.nih.gov/pubmed/22053079 http://dx.doi.org/10.1093/nar/gkr871 |
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