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Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability
Microsatellite DNA synthesis represents a significant component of human genome replication that must occur faithfully. However, yeast replicative DNA polymerases do not possess high fidelity for microsatellite synthesis. We hypothesized that the structural features of Y-family polymerases that faci...
Autores principales: | Hile, Suzanne E., Wang, Xiaoxiao, Lee, Marietta Y. W. T., Eckert, Kristin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287198/ https://www.ncbi.nlm.nih.gov/pubmed/22021378 http://dx.doi.org/10.1093/nar/gkr889 |
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