A human XRCC4–XLF complex bridges DNA

DNA double-strand breaks pose a significant threat to cell survival and must be repaired. In higher eukaryotes, such damage is repaired efficiently by non-homologous end joining (NHEJ). Within this pathway, XRCC4 and XLF fulfill key roles required for end joining. Using DNA-binding and -bridging ass...

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Detalles Bibliográficos
Autores principales: Andres, Sara N., Vergnes, Alexandra, Ristic, Dejan, Wyman, Claire, Modesti, Mauro, Junop, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287209/
https://www.ncbi.nlm.nih.gov/pubmed/22287571
http://dx.doi.org/10.1093/nar/gks022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287209/
https://www.ncbi.nlm.nih.gov/pubmed/22287571
http://dx.doi.org/10.1093/nar/gks022

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