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Clusterin is a potential molecular predictor for ovarian cancer patient's survival: targeting Clusterin improves response to paclitaxel

BACKGROUND: Clusterin is a cytoprotective chaperone protein involved in numerous physiological processes, carcinogenesis, tumor growth and tissue remodelling. The purpose of this study was to investigate whether clusterin (CLU), an antiapoptotic molecule, could be a potential predictor molecule for...

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Detalles Bibliográficos
Autores principales: Hassan, Mohamed K, Watari, Hidemichi, Han, Yimin, Mitamura, Takashi, Hosaka, Masayoshi, Wang, Lei, Tanaka, Shinya, Sakuragi, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287343/
https://www.ncbi.nlm.nih.gov/pubmed/22185350
http://dx.doi.org/10.1186/1756-9966-30-113