Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation

Survivin is a critical regulator of mitosis, and an inhibitor of apoptosis which is overexpressed in almost all cancers. In the current study, cell cycle profiles of normal proliferating human umbilical vein endothelial cells, prostate cancer, and lung cancer cell lines expressing varying levels of...

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Detalles Bibliográficos
Autores principales: Jacob, Naduparambil K, Cooley, James V, Shirai, Katsuyuki, Chakravarti, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287415/
https://www.ncbi.nlm.nih.gov/pubmed/22375097
http://dx.doi.org/10.2147/OTT.S28147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287415/
https://www.ncbi.nlm.nih.gov/pubmed/22375097
http://dx.doi.org/10.2147/OTT.S28147

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