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Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation
Survivin is a critical regulator of mitosis, and an inhibitor of apoptosis which is overexpressed in almost all cancers. In the current study, cell cycle profiles of normal proliferating human umbilical vein endothelial cells, prostate cancer, and lung cancer cell lines expressing varying levels of...
Autores principales: | Jacob, Naduparambil K, Cooley, James V, Shirai, Katsuyuki, Chakravarti, Arnab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287415/ https://www.ncbi.nlm.nih.gov/pubmed/22375097 http://dx.doi.org/10.2147/OTT.S28147 |
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