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A new protein-ligand binding sites prediction method based on the integration of protein sequence conservation information
BACKGROUND: Prediction of protein-ligand binding sites is an important issue for protein function annotation and structure-based drug design. Nowadays, although many computational methods for ligand-binding prediction have been developed, there is still a demanding to improve the prediction accuracy...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287474/ https://www.ncbi.nlm.nih.gov/pubmed/22373099 http://dx.doi.org/10.1186/1471-2105-12-S14-S9 |