Cargando…

A methodology for multivariate phenotype-based genome-wide association studies to mine pleiotropic genes

BACKGROUND: Current Genome-Wide Association Studies (GWAS) are performed in a single trait framework without considering genetic correlations between important disease traits. Hence, the GWAS have limitations in discovering genetic risk factors affecting pleiotropic effects. RESULTS: This work repor...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Sung Hee, Lee, Ji Young, Kim, Sangsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287479/
https://www.ncbi.nlm.nih.gov/pubmed/22784570
http://dx.doi.org/10.1186/1752-0509-5-S2-S13