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Changes in predicted protein disorder tendency may contribute to disease risk
BACKGROUND: Recent studies suggest that many proteins or regions of proteins lack 3D structure. Defined as intrinsically disordered proteins, these proteins/peptides are functionally important. Recent advances in next generation sequencing technologies enable genome-wide identification of novel nucl...
Autores principales: | Hu, Yang, Liu, Yunlong, Jung, Jeesun, Dunker, A Keith, Wang, Yadong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287498/ https://www.ncbi.nlm.nih.gov/pubmed/22369681 http://dx.doi.org/10.1186/1471-2164-12-S5-S2 |
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