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Predicting sequence and structural specificities of RNA binding regions recognized by splicing factor SRSF1

BACKGROUND: RNA-binding proteins (RBPs) play diverse roles in eukaryotic RNA processing. Despite their pervasive functions in coding and noncoding RNA biogenesis and regulation, elucidating the sequence specificities that define protein-RNA interactions remains a major challenge. Recently, CLIP-seq...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Juan, Liran, Lv, Junjie, Wang, Kejun, Sanford, Jeremy R, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287504/
https://www.ncbi.nlm.nih.gov/pubmed/22369183
http://dx.doi.org/10.1186/1471-2164-12-S5-S8