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Statistical methods on detecting differentially expressed genes for RNA-seq data
BACKGROUND: For RNA-seq data, the aggregated counts of the short reads from the same gene is used to approximate the gene expression level. The count data can be modelled as samples from Poisson distributions with possible different parameters. To detect differentially expressed genes under two situ...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287564/ https://www.ncbi.nlm.nih.gov/pubmed/22784615 http://dx.doi.org/10.1186/1752-0509-5-S3-S1 |