Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach

We propose a nonparametric Bayes-based clustering algorithm to detect associations with rare and common single-nucleotide polymorphisms (SNPs) for quantitative traits. Unlike current methods, our approach identifies associations with rare genetic variants at the variant level, not the gene level. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Lili, Baye, Tesfaye M, He, Hua, Zhang, Xue, Kurowski, Brad G, Martin, Lisa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287822/
https://www.ncbi.nlm.nih.gov/pubmed/22373351
http://dx.doi.org/10.1186/1753-6561-5-S9-S10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287822/
https://www.ncbi.nlm.nih.gov/pubmed/22373351
http://dx.doi.org/10.1186/1753-6561-5-S9-S10

Ejemplares similares