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A LASSO-based approach to analyzing rare variants in genetic association studies

Genetic markers with rare variants are spread out in the genome, making it necessary and difficult to consider them in genetic association studies. Consequently, wisely combining rare variants into “composite” markers may facilitate meaningful analyses. In this paper, we propose a novel approach of...

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Detalles Bibliográficos
Autores principales: Brennan, Jennifer S, He, Yunxiao, Calixte, Rose, Nyirabahizi, Epiphanie, Jiang, Yuan, Zhang, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287823/
https://www.ncbi.nlm.nih.gov/pubmed/22373373
http://dx.doi.org/10.1186/1753-6561-5-S9-S100