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Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach
Both common variants and rare variants are involved in the etiology of most complex diseases in humans. Developments in sequencing technology have led to the identification of a high density of rare variant single-nucleotide polymorphisms (SNPs) on the genome, each of which affects only at most 1% o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287829/ https://www.ncbi.nlm.nih.gov/pubmed/22373536 http://dx.doi.org/10.1186/1753-6561-5-S9-S106 |