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Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach

Both common variants and rare variants are involved in the etiology of most complex diseases in humans. Developments in sequencing technology have led to the identification of a high density of rare variant single-nucleotide polymorphisms (SNPs) on the genome, each of which affects only at most 1% o...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Huang, Chien Hsun, Hu, Inchi, Lo, Shaw-Hwa, Zheng, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287829/
https://www.ncbi.nlm.nih.gov/pubmed/22373536
http://dx.doi.org/10.1186/1753-6561-5-S9-S106