Successful identification of rare variants using oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies

We aim to identify rare variants that have large effects on trait variance using a cost-efficient strategy. We use an oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies to identify families more likely to harbor rare variants, by estimating the mean number of q...

Descripción completa

Detalles Bibliográficos
Autores principales: Gagnon, France, Roslin, Nicole M, Lemire, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287833/
https://www.ncbi.nlm.nih.gov/pubmed/22373114
http://dx.doi.org/10.1186/1753-6561-5-S9-S11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287833/
https://www.ncbi.nlm.nih.gov/pubmed/22373114
http://dx.doi.org/10.1186/1753-6561-5-S9-S11

Ejemplares similares