Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants?

Use of trait-dependent sampling designs in whole-genome association studies of sequence data can reduce total sequencing costs with modest losses of statistical efficiency. In a quantitative trait (QT) analysis of data from the Genetic Analysis Workshop 17 mini-exome for unrelated individuals in the...

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Detalles Bibliográficos
Autores principales: Yilmaz, Yildiz E, Bull, Shelley B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287835/
https://www.ncbi.nlm.nih.gov/pubmed/22373146
http://dx.doi.org/10.1186/1753-6561-5-S9-S111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287835/
https://www.ncbi.nlm.nih.gov/pubmed/22373146
http://dx.doi.org/10.1186/1753-6561-5-S9-S111

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