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Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants?

Use of trait-dependent sampling designs in whole-genome association studies of sequence data can reduce total sequencing costs with modest losses of statistical efficiency. In a quantitative trait (QT) analysis of data from the Genetic Analysis Workshop 17 mini-exome for unrelated individuals in the...

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Detalles Bibliográficos
Autores principales:	Yilmaz, Yildiz E, Bull, Shelley B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287835/ https://www.ncbi.nlm.nih.gov/pubmed/22373146 http://dx.doi.org/10.1186/1753-6561-5-S9-S111

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