Effect of population stratification analysis on false-positive rates for common and rare variants

Principal components analysis (PCA) has been successfully used to correct for population stratification in genome-wide association studies of common variants. However, rare variants also have a role in common disease etiology. Whether PCA successfully controls population stratification for rare vari...

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Detalles Bibliográficos
Autores principales: He, Hua, Zhang, Xue, Ding, Lili, Baye, Tesfaye M, Kurowski, Brad G, Martin, Lisa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287840/
https://www.ncbi.nlm.nih.gov/pubmed/22373282
http://dx.doi.org/10.1186/1753-6561-5-S9-S116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287840/
https://www.ncbi.nlm.nih.gov/pubmed/22373282
http://dx.doi.org/10.1186/1753-6561-5-S9-S116

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