Identifying rare disease variants in the Genetic Analysis Workshop 17 simulated data: a comparison of several statistical approaches

Genome-wide association studies have been successful at identifying common disease variants associated with complex diseases, but the common variants identified have small effect sizes and account for only a small fraction of the estimated heritability for common diseases. Theoretical and empirical...

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Detalles Bibliográficos
Autores principales: Fan, Ruixue, Huang, Chien-Hsun, Lo, Shaw-Hwa, Zheng, Tian, Ionita-Laza, Iuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287851/
https://www.ncbi.nlm.nih.gov/pubmed/22373071
http://dx.doi.org/10.1186/1753-6561-5-S9-S17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287851/
https://www.ncbi.nlm.nih.gov/pubmed/22373071
http://dx.doi.org/10.1186/1753-6561-5-S9-S17

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