Interrogating population structure and its impact on association tests

We found from our analysis of the Genetic Analysis Workshop 17 data that the population structure of the 697 unrelated individuals was an important confounding factor for association studies, even if it was not explicitly considered when simulating the phenotypes. We uncovered structures beyond the...

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Detalles Bibliográficos
Autores principales: Qin, Huaizhen, Elston, Robert C, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287860/
https://www.ncbi.nlm.nih.gov/pubmed/22373290
http://dx.doi.org/10.1186/1753-6561-5-S9-S25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287860/
https://www.ncbi.nlm.nih.gov/pubmed/22373290
http://dx.doi.org/10.1186/1753-6561-5-S9-S25

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