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Comparison of genetic association strategies in the presence of rare alleles
In the quest for the missing heritability of most complex diseases, rare variants have received increased attention. Advances in large-scale sequencing have led to a shift from the common disease/common variant hypothesis to the common disease/rare variant hypothesis or have at least reopened the de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287868/ https://www.ncbi.nlm.nih.gov/pubmed/22373505 http://dx.doi.org/10.1186/1753-6561-5-S9-S32 |