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Comparison of genetic association strategies in the presence of rare alleles

In the quest for the missing heritability of most complex diseases, rare variants have received increased attention. Advances in large-scale sequencing have led to a shift from the common disease/common variant hypothesis to the common disease/rare variant hypothesis or have at least reopened the de...

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Detalles Bibliográficos
Autores principales: Mahachie John, Jestinah M, Cattaert, Tom, De Lobel, Lizzy, Van Lishout, François, Empain, Alain, Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287868/
https://www.ncbi.nlm.nih.gov/pubmed/22373505
http://dx.doi.org/10.1186/1753-6561-5-S9-S32