Comparative study of statistical methods for detecting association with rare variants in exome-resequencing data

Genome-wide association studies for complex traits are based on the common disease/common variant (CDCV) and common disease/rare variant (CDRV) assumptions. Under the CDCV hypothesis, classical genome-wide association studies using single-marker tests are powerful in detecting common susceptibility...

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Detalles Bibliográficos
Autores principales: Saad, Mohamad, Pierre, Aude Saint, Bohossian, Nora, Macé, Matthias, Martinez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287869/
https://www.ncbi.nlm.nih.gov/pubmed/22373523
http://dx.doi.org/10.1186/1753-6561-5-S9-S33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287869/
https://www.ncbi.nlm.nih.gov/pubmed/22373523
http://dx.doi.org/10.1186/1753-6561-5-S9-S33

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