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Comparative study of statistical methods for detecting association with rare variants in exome-resequencing data
Genome-wide association studies for complex traits are based on the common disease/common variant (CDCV) and common disease/rare variant (CDRV) assumptions. Under the CDCV hypothesis, classical genome-wide association studies using single-marker tests are powerful in detecting common susceptibility...
Autores principales: | Saad, Mohamad, Pierre, Aude Saint, Bohossian, Nora, Macé, Matthias, Martinez, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287869/ https://www.ncbi.nlm.nih.gov/pubmed/22373523 http://dx.doi.org/10.1186/1753-6561-5-S9-S33 |
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