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Family- and population-based designs identify different rare causal variants

Both family- and population-based samples are used to identify genetic variants associated with phenotypes. Each strategy has demonstrated advantages, but their ability to identify rare variants and genes containing rare variants is unclear. To compare these two study designs in the identification o...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, He, Hua, Ding, Lili, Baye, Tesfaye M, Kurowski, Brad G, Martin, Lisa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287872/
https://www.ncbi.nlm.nih.gov/pubmed/22373077
http://dx.doi.org/10.1186/1753-6561-5-S9-S36