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Family- and population-based designs identify different rare causal variants
Both family- and population-based samples are used to identify genetic variants associated with phenotypes. Each strategy has demonstrated advantages, but their ability to identify rare variants and genes containing rare variants is unclear. To compare these two study designs in the identification o...
Autores principales: | Zhang, Xue, He, Hua, Ding, Lili, Baye, Tesfaye M, Kurowski, Brad G, Martin, Lisa J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287872/ https://www.ncbi.nlm.nih.gov/pubmed/22373077 http://dx.doi.org/10.1186/1753-6561-5-S9-S36 |
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