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Identification of genes and variants associated with quantitative traits using Bayesian factor screening

We propose a factor-screening method based on a Bayesian model selection framework and apply it to Genetic Analysis Workshop 17 simulated data with unrelated individuals to identify genes and SNP variants associated with the quantitative trait Q1. A Metropolis-Hasting algorithm is implemented to gen...

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Detalles Bibliográficos
Autores principales: Pradhan, Kith, Yoon, Seungtai Chris, Wang, Tao, Ye, Kenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287876/
https://www.ncbi.nlm.nih.gov/pubmed/22373183
http://dx.doi.org/10.1186/1753-6561-5-S9-S4