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Comparison of SNP-based and gene-based association studies in detecting rare variants using unrelated individuals

We compare the SNP-based and gene-based association studies using 697 unrelated individuals. The Benjamini-Hochberg procedure was applied to control the false discovery rate for all the multiple comparisons. We use a linear model for the single-nucleotide polymorphism (SNP) based association study....

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Detalles Bibliográficos
Autores principales: Tong, Liping, Tayo, Bamidele, Yang, Jie, Cooper, Richard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287878/
https://www.ncbi.nlm.nih.gov/pubmed/22373242
http://dx.doi.org/10.1186/1753-6561-5-S9-S41