Cargando…

Methods for detecting associations between phenotype and aggregations of rare variants

Although genome-wide association studies have uncovered variants associated with more than 150 traits, the percentage of phenotypic variation explained by these associations remains small. This has led to the search for the dark matter that explains this missing genetic component of heritability. On...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Fan, Kang, Chul Joo, Marjoram, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287889/
https://www.ncbi.nlm.nih.gov/pubmed/22373540
http://dx.doi.org/10.1186/1753-6561-5-S9-S51